Glutathione, which is naturally present in the human body, performs a great many functions that are important for health. What matters above all is the active form, reduced glutathione. The body's own reduced glutathione is one of the most important antioxidants of all.
Since, in the case of a glutathione deficiency, it is difficult to replenish glutathione levels in the cell “from outside”, Dr. med. Ohlenschläger developed the pharmaceutical active substance S-acetyl-glutathione (SAG). With this active substance it is possible to raise intracellular glutathione levels medically, effectively and sustainably.
In this way, S-acetyl-glutathione can exert in the body the same positive effects that the body's own reduced glutathione has.
Positive effects of SAG in Eumetabol®
- It modulates the immune system and thereby ensures healthy defence responses against viruses, fungi and other pathogens.
- It has antiviral effects via several pathways.
- It regulates inflammation.
- It promotes the provision of energy and can therefore also relieve post-viral fatigue (e.g. in post-COVID syndrome).
- It prevents damage to cells and important cell structures.
- It is a chelating agent (chelator) that eliminates heavy metals.
- It also has a general detoxifying effect in other respects.
- It protects against chronic diseases.
- It inhibits physiological ageing processes.
S-acetyl-glutathione (Eumetabol®) and the immune system
Glutathione strengthens the immune system through various mechanisms:
- Controls inflammation: certain inflammations are important for the body's defences, because they kill viruses and bacteria. Other inflammatory processes harm the body. Glutathione helps to ensure that substances are produced which regulate inflammation in such a way that it benefits the body rather than harming it.
- Activates lymphocytes: glutathione activates lymphocytes, a particular type of white blood cell that is especially important for immune defence. Lymphocytes can even destroy cancer cells. Lymphocytes include, for example, the so-called NK cells (natural killer cells).
- Inhibits the risk of infection: as a redox buffer, glutathione inhibits the entry of pathogens into the cells and thus infection.
- Ensures a healthy immune balance: glutathione is necessary so that the body can correctly “identify” the respective pathogens and initiate the right defence strategies.
- Has an antiviral effect: glutathione hinders viral replication in the host cell by altering certain signalling pathways in the pathogens.
S-acetyl-glutathione (Eumetabol®) and energy or performance
Glutathione increases energy and performance by supporting the energy balance in several ways:
- Cellular power plants: in the mitochondria, the “power plants of the cell”, ATP is produced, a central energy carrier for all living beings. Free radicals are generated during its production. Only if these are “defused” by glutathione can energy continue to be produced.
- Oxygen supply: glutathione protects the red blood pigment haemoglobin from oxidation. Only in this way can haemoglobin transport oxygen through the body. If oxygen transport is impaired, the result is reduced performance, tiredness, exhaustion and shortness of breath.
S-acetyl-glutathione (Eumetabol®) and cell protection
Glutathione is of the utmost importance for the organism in maintaining healthy cell functions:
- Super antioxidant: glutathione renders free radicals and peroxides harmless. These are very aggressive molecules that damage the body's molecules by “stealing” electrons from them. Victims include, for example, the body's own proteins, enzymes, cell membranes or genes (DNA).
- DNA repair: glutathione can “repair” damaged genes. This applies both to the genetic information of the DNA in the cell nucleus and to the DNA within the “cellular power plants”, the mitochondria.
- Cell division: glutathione helps to control healthy cell growth and healthy cell division.
- Cell metabolism: glutathione plays a decisive part in cell metabolism. For example, it helps to transport important substances across the cell membrane. Glutathione is also important for the specialisation of cells for particular tasks, so that the body functions.
- Support for other antioxidants: glutathione is not only a super antioxidant itself. It can also recycle or reactivate other antioxidants once they have been used up. A great many other antioxidants can only function properly if enough glutathione is present.
Glutathione can “recycle” these radical scavengers, among others:
- Coenzyme Q10
- Flavonoids
- Provitamin A
- Selenium
- Vitamin C
- Vitamin E
S-acetyl-glutathione (Eumetabol®) and detoxification
The glutathione system is regarded as the body's most important detoxification system. It is crucial for many detox processes:
- Elimination of environmental toxins and heavy metals: glutathione is very good at binding toxins to itself. The pollutants “captured” by glutathione can easily be transported away and excreted via the liver and the kidneys.
- Elimination of the body's own harmful substances: in the same way, glutathione detoxifies waste products that arise during natural metabolism. These too can cause damage. Glutathione ensures that these toxins are also transported away.
- Elimination of other harmful substances: even substances taken in voluntarily can harm people. Examples are alcohol, nicotine or certain breakdown products of medicines. Such substances cause health problems if they are not rendered harmless. Glutathione “captures” these toxins and ensures that they are excreted.
S-acetyl-glutathione (Eumetabol®) and health in general
- Glutathione protects against acute infections and possible secondary damage (e.g. Long COVID) by generally supporting the body's defences and regulating inflammation.
- As an antioxidant, glutathione can protect against (secondary) diseases such as arteriosclerosis, high blood pressure, other cardiovascular problems, diabetes, Parkinson's, Alzheimer's, rheumatism, arthritis, cancer and much more. For all of these diseases, mechanisms of development are being discussed on which glutathione has a positive effect, so that the risk of disease falls.
- Glutathione is involved in vital metabolic processes.
- Without glutathione, important endogenous enzymes cannot perform their detoxification function (a further way in which glutathione promotes detoxification!).
- As a radical scavenger, glutathione ensures that age-related degenerative processes are slowed down.
- As a “detoxifier”, glutathione prevents the consequences of exposure to pollutants and can transport heavy metals out of the body. In this way it can have a positive influence on autoimmune diseases or hyperactivity, among other things.
S-acetyl-glutathione of unique quality
Eumetabol®: this name stands for the highest effectiveness in glutathione therapy. Eumetabol® was originally developed to treat cancer-related exhaustion medically. Today, glutathione cell therapy is used successfully wherever new strength is needed, e.g. in
- post-viral exhaustion syndromes, e.g. Long COVID
- exhaustion after stress
- burnout
- chronic fatigue syndrome
Other important areas of application are immunomodulation, the accompanying therapy of acute infections, chelation therapy for eliminating harmful metals from the body, and numerous other health problems associated with a glutathione deficiency (GSH deficiency). Since the S-acetyl-glutathione in Eumetabol® also has a preventive effect, Eumetabol® is also used successfully for general preventive health care and performance enhancement. Eumetabol®: live healthier, full of energy
The demonstrably most effective glutathione therapy
What makes Eumetabol® special is its unique quality. Eumetabol® is the only preparation that contains the active substance S-acetyl-glutathione according to Dr. med. Gerhard Ohlenschläger®. This special S-acetyl-glutathione (SAG) is an active substance of pharmaceutical quality.
The active substance of every single Eumetabol® batch is subject to the strictest quality testing by PharmBioTec GmbH. In this testing laboratory, the active substance of Eumetabol® is tested for its purity and content using established and validated analytical methods and in accordance with the requirements of medicines law. We can therefore guarantee the outstanding quality of Eumetabol®.
With S-acetyl-glutathione according to Dr. med. Gerhard Ohlenschläger® it is possible to increase the glutathione level within the cells, and to do so effectively, sustainably and safely. Clinical experience has convincingly demonstrated the positive effect of Eumetabol® compared with other glutathione preparations.
Why does SAG work better than “normal” reduced glutathione?
With a half-life of 1.6 minutes, “normal” reduced glutathione cannot be used therapeutically in any meaningful way to increase intracellular glutathione levels. Studies have demonstrated this. Yet it is precisely these values, within the cell, that are decisive for almost all health effects of a glutathione therapy. The solution is offered by the individually usable Eumetabol® infusions.
After administration of “normal” reduced glutathione (GSH), glutathione can no longer be detected in the blood after only about 10 minutes. The infused GSH becomes ineffective through oxidation within a very short time. After administration of SAG (Eumetabol®), the level of the active substance in the blood is still so high after around one hour that it can exert a sustained therapeutic effect.

